The AD-IMDB database is a curated resource dedicated to the reconstruction and annotation of microbial genomes from a catalogue of shotgun metagenomic data related to Alzheimer's disease mouse models. The original dataset relative to 3xTg-AD mice was published and described in Favero et al., Biol Direct, 2024 (PMID: 39478626). Here, we implemented a computational pipeline for the ab initio reconstruction of both known and unknown genomes from raw sequencing data, followed by a targeted computational analysis of the annotated proteins. The AD-IMDB database provides access to the complete set of genomes and proteins, along with their functional annotations.
The AD-IMDB database provides 3 main functionalities:
- Explore Genomes
- Explore Protein Annotations
- Access Downloads
